ABSTRACT
OBJECTIVE: to evaluate the serum level of Alkaline Phosphatase, Creatine Phosphokinase and Calcium level in patients suffering from chronic periodontitis.
MATERIALS AND METHODS : In this study a cross sectional analysis of 40 male and 40 female subjects suffering from chronic periodontitis was conducted to assess the associated risk in term of bone loss and cardiovascular diseases by measuring serum Alkaline Phosphatase(ALP), Creatine Phosphokinase(CPK) and Calcium level.
RESULTS: A higher mean level of ALP in both population group (Male: 195.45 U/I, Female: 203.92 U/I) was observed than normal level (52-192 U/I). The mean value of CPK was observed to be within the normal ranges for both groups (Normal: 26-171 U/I) (Male: 143.82 U/I; Female: 122.58 U/I) but was higher for male population than the female population. The mean value of Ca was found to be 10.12 mg/dL for male subjects and 10.28 mg/dL for female subjects (Normal level: 8.7-10.4 mg/dL).
CONCLUSIONS: The results of our study suggests that female subjects are at greater risk of periodontitis and alveolar bone degradation in term of mean values of serum ALP and Ca than the male subjects while the higher mean values of serum CPK in male subjects put them at higher risk of cardio vascular disease than the female subjects.
Key words: Alkaline Phosphatase, Creatine Phosphokinase, periodontitis, Calcium
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