Background: Prion and Prion diseases are incurable neurodegenerative conditions that are sporadic, infectious and
inherited in origin and extremely resistant to conventional sterilization procedures, hence can be potential risk to
health care professionals especially nurses and dentists. Aim: This baseline KAP study is aimed to assess the
knowledge about prion and prion diseases among dental and nursing students. Objectives: The primary objective
is to assess the knowledge about these diseases among dental and nursing students and the secondary objective is
to assess the attitude about this topic among the same fraternities. Materials & Methods: An interventional cross
sectional descriptive baseline KAP (Knowledge, attitude and practice) study was conducted among 300 students
(150 dental & 150 nursing) from Western Maharashtra. Information regarding the sociodemographic variables
were collected from the participants. A prestructured and validated, pre / post test questionnaires with open ended
and close ended questions was prepared. Intervention using a brief power point presentation on prion and its
diseases was taken for all the participants. The data collected was subjected to SPSS version 10 for statistical
analysis. Results: The mean difference of about 3.7 ± 1.3 (pre test) and 9.0±0.8 (post test) was noted among
nursing students whereas the mean difference of about 3.6 ±1.2 (pre test) and 9.2 ±0.7 (post test) was noted
among dental students. Conclusion: Lack of awareness of Prion and prion diseases has highlighted the need to
introduce this topic among health care professionals as well as create awareness regarding the sterilization
methods to be adopted for such cases.
Prion, Prion diseases, Knowledge, Attitude, Nursing faculty, Dental faculty
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