Objective: To investigate seroprevalence of Human Immunodeficiency Virus (HIV) among injection drug users (IDUs) at District Sanghar, Pakistan.
Methodology: A total of 119 blood samples were collected from IDUs shooting drugs at different sites across District Sanghar. Demographic data regarding age, gender, marital status, education, and occupation were collected. Presence of HIV was detected using 4th Generation immunochromatographic Alere Combo kits Ag/Ab HIV-1/2 as per manufacturer’s instructions.
Results: We found that 24(20.17%) samples were positive for HIV infection. Among them, male IDUs were 22(18.49%), while 2(1.68%) were female IDUs. Taluka-wise frequency of HIV among IDUs revealed that highest cases 10.08% (n=12) in taluka Tando Adam, followed by taluka Shahdadpur having 5.88% (n=07) cases. Taluka Sanghar had 3.36% (n=04) cases while least number of positive cases was found in taluka Sinjhoro 0.8% (n=01).
Conclusion: HIV was more prevalent in male IDUs as compared to female. High prevalence of HIV among IDUs in district Sanghar is alarming and warrants urgent attention of health professionals for strict measures to control the transmission of HIV in IDUs and general population.
Seroprevalence, injecting drug users, HIV, AIDS.
Integrated molecular and affiliation network analysis: Core-periphery social clustering is associated with HIV transmission patterns.
Fujimoto K, Paraskevis D, Kuo JC, Hallmark CJ, Zhao J, Hochi A, Kuhns LM, Hwang LY, Hatzakis A, Schneider JA
Social networks. 2022; 68(): 107-117
Performance Comparison of Five SARS-CoV-2 Antibody Assays for Seroprevalence Studies.
Park Y, Hong KH, Lee SK, Hyun J, Oh EJ, Lee J, Lee H, Song SH, Kee SJ, Kwon GC, Kim SH, Do HN, Kim AR, Lee JW, Kim SS, Kim HS
Annals of laboratory medicine. 2022; 42(1): 71-78
3D and 4D Tumorigenesis Model for the Quantitative Analysis of Cancer Cell Behavior and Screening for Anticancer Drugs.
Wessels D, Lusche DF, Voss E, Soll DR
Methods in molecular biology (Clifton, N.J.). 2022; 2364(): 299-318
Turbidity-Based MIC Assay and Characterization of Spontaneous Drug Resistant Mutants in Mycobacterium ulcerans.
Thomas SS, Kalia NP, Pethe K
Methods in molecular biology (Clifton, N.J.). 2022; 2387(): 209-217
Drug Efficacy Testing in the Mouse Footpad Model of Buruli Ulcer.
Converse PJ, Almeida DV, Nuermberger EL
Methods in molecular biology (Clifton, N.J.). 2022; 2387(): 195-207