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Research Article

JCDR. 2021; 12(3): 1051-1053

Role of Curcumin Adminisration on Experimentally Induced Nonalcoholic Steatohepatitis (NASH)

Nahla Mohammed Abd El-Hameed, Azza Hussein Ali, Hanna Hassanein mohammed, Mahmoud A. khattab,Seham A Abd El-Aleem.


Background: The strong association of NASH with sedentary lifestyle and dietary habits drives the need for further investigations. Curcumin is a natural herbal believed to be hepatoprotective.
Aim: To study curcumin as a prophylactic agent in NAFLD rat model.
Material and Methods: thirty rats were allocated into 3 groups. Normal control, high fat diet (HFD) and the prophylactic groups. HFD regimen was given for 4 months. Curcumin was given as a prophylactic along with HFD. Livers were harvested and processed for histological study.
Conclusions: Curcumin has an efficient protection and hindering of the development of NASH and could be recommended in NASH susceptible people.

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