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Implant Failure and Changes Between Regenerative Procedure Group and Control Group: A Systematic Review and Meta-analysis

Ali Amiri, Aziz Goshaderoo, Pantea Moradinejad, Mohammad Shokri Vahed, Fan Qi.


Objective: In the esthetic area, immediate implant placement are a great opportunity in modern dentistry. Nevertheless, the outcome was impacted by numerous surgical and prosthetic components. This systematic review and meta-analysis aimed to evaluate immediate implant failure and changes between the regenerative procedure and control groups.
Methods: MEDLINE, PubMed, Cochrane Library, Embase, ISI, and Google scholar have been utilized as the electronic databases for performing a systematic literature review between 2010 to March 2021. The quality of the involved studies has been evaluated using the Cochrane tool and assessed by two reviewers. The current systematic review has been carried out with regard to the key consideration of the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA). The mean difference was used for changes in the crestal bone between baseline and follow-up. Risk ratio with the 95% confidence interval (CI) used for implant failure between test and control groups.
Results: 126 potentially relevant titles and abstracts were found during the electronic search. Finally, four publications fulfilled the inclusion criteria required for this systematic review. The Mean difference of changes in the crestal bone between test and control groups of immediate implant placement was 0.62mm (95% CI: 0.31mm, 0.94mm; P=0.00) and heterogeneity found (I2 = 80.43%; P =0.00).
Conclusions: The immediately placed implants with regenerative procedure versus the control group showed the better performance to the changes in the crestal bone.

Key words: Alveolar Bone Grafting, Dental Implantation, Dental Prosthesis

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