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Case Report

Wernicke's encephalopathy: rare complication of hyperemesis gravidarum

Ayoub Ettabyaoui, Hiba Oudghiri, Otman El Ouarti, Badr Alami, Nizar Bouardi, Meriem Haloua, My Youssef Lamrani Alaoui, Meryem Boubbou, Mustapha Maaroufi.

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Wernicke’s encephalopathy is a rare disease resulting from severe thiamine deficiency
(vitamin B1). Alcoholic subjects are most often affected, but it may occur outside
of this addiction.
Magnetic resonance imaging is the gold standard imaging modality to confirm the diagnosis. This pathology manifests in T2-weighted hyperintensity in the periaqueductal, thalami and mammillary bodies. A suitable treatment makes it possible to avoid heavy sequelae.
We report the case of a 23-year-old woman, pregnant with 12 weeks of amenorrhea, with diplopia, headache and abundant vomiting, referring to Wernicke’s encephalopathy.

Key words: Gayet Wernicke’s encephalopathy, vomiting during pregnancy, vitamin B1

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