Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles
 

Open Access

Review Article



Immunomodulatory activities of five clinically used Chinese herbal polysaccharides

Xiaojuan He, Xuyan Niu, Jian Li, Shaohua Xu, Aiping Lu.

Cited by (13)

Abstract
Polysaccharide is a natural macromolecular compound with complex, important and multifaceted biological activities. Some of polysaccharides have been marketed in China as drugs or healthy products.
More studies confirm that the active ingredient of many traditional Chinese medicine exist in the form of polysaccharides. They play a role in disease therapy by activating immune cells and the complement system; regulating the cytokines expression; promoting the production of antibodies; inhibiting tumor cell proliferation and inducing tumor cell apoptosis; inhibiting virus entering cells and replication; increasing activity of antioxidant enzyme; scavenging free radicals; and inhibiting lipid peroxidation.
In this review, we focus on the immunomodulatory effects and its possible mechanism of polysaccharides from Chinese herbal polysaccharides products, including Lentinan, Astragalus polysaccharide, Polyporus polysaccharide and Achyranthes bidentata polysaccharide. The immunomodulatory activities of polysaccharides were categorized in the paper into general immunoregulatory activity, anti-tumor, anti-infections, anti-inflammatory, anti-oxidative, anti-mutagenic and radioprotective, anti-complementary, anti-adhesive, and anti-allergy since all the activities are related to modulate immune responses by the polysaccharides. Also the challenges in the research of polysaccharides will be discussed.

Key words: Chinese herbal medicine; Immunomodulatory activity; Polysaccharides



Similar Articles

Improving cell transplantation by understanding and manipulating the phagocytic activity of peripheral glia.
Nazareth L, St John J, Ekberg J
Neural regeneration research. 2022; 17(2): 313-314

Health technology assessment and economic evaluation: Is it applicable for the traditional medicine?
Chen Y
Integrative medicine research. 2022; 11(1): 100756

Exploring the potential application of dental pulp stem cells in neuroregenerative medicine.
Sultan N, Scheven BA
Neural regeneration research. 2022; 17(4): 775-776

Induced pluripotent stem cells for defining Parkinsonian patient subtypes: a further step toward precision medicine.
Bono F, Missale C, Fiorentini C
Neural regeneration research. 2022; 17(4): 767-769

Significance of mitochondrial activity in neurogenesis and neurodegenerative diseases.
Ozgen S, Krigman J, Zhang R, Sun N
Neural regeneration research. 2022; 17(4): 741-747


Full-text options


Latest Statistics about COVID-19
• pubstat.org


Add your Article(s) to Indexes
• citeindex.org






Covid-19 Trends and Statistics
ScopeMed.com
CiteIndex.org
CancerLine
FoodsLine
PhytoMedline
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.



ScopeMed Web Sites