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Research Article

. 2021; 12(3): 1043-1055


Impact of Diet and Intestinal Microbiome on Neurodegenerative Diseases

Fatma Nur Güleç, Ismail A. Elhaty.

Abstract
Diet plays an important role in the health of the individuals such as determining the composition of the gut microbiome. It has been reported that neurodegenerative diseases are associated with changes in diet and the gut microbiome and its metabolites. The balance of bacteria in the intestinal microbiota provides health benefits to the host, and its imbalance plays a role in the development of various diseases, especially neurological diseases, by creating dysbiosis. It also has been observed that beneficial bacteria can prevent or cure the development of neurological diseases by repairing this dysbiosis.
In this review, we discuss how neurological diseases occur, the mechanism of suspicious triggers, the relationship between the intestinal microbiota and neurodegenerative diseases, and whether these diseases can be treated according to diet

Key words: Diet; Intestinal; Microbiome; Neurodegenerative; Polyphenols.



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