Home|Journals|Articles by Year

Directory for Medical Articles
 

Research Article

JCDR. 2022; 13(2): 59-63


Transdermal patches of buprenorphine (10mg) and diclofenac (200mg) for of post-operative analgesia: adverse effects and patient satisfaction

Dr.Neeta Kulkarni,Dr.Lokesh SB,Dr.Geetha M.


Abstract

Buprenorphine is a highly lipophilic semisynthetic opioid.it is derived from thebaine, a morphine opioid.
Buprenorphine is a partial agonist at μ opioid receptors which has high affinity but moderate intrinsic
activity. Buprenorphine is also an antagonist at kappa-opioid receptors and delta -opioid receptors, and a
partial agonist at ORL-1 (nociceptin) receptors. Following ethics committee approval, informed written
consent was obtained from the patients. Detailed pre-anaesthetic evaluation was done. Demographic
(age, gender), morphological (height, weight) and vital parameters were recorded. In our study 7 patients
in Buprenorphine group had nausea/vomiting and one patient was drowsy but arousable whereas in
Diclofenac group 4 patients had nausea and none of the patients were sedated during the entire study
period.

Key words: Transdermal patches, buprenorphine, diclofenac






Full-text options


Share this Article



Online Article Submission
• ejmanager.com
• ojshosting.net







Do you want to use OJS for your journal ?
work with an experienced partner
www.OJSHosting.net

eJManager.com
Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.