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Neutrophil-to-lymphocyte and basophil-to-lymphocyte ratios in children with adenoid vegetation: Can they be prognostic markers?

Mumtaz Taner Torun.




Abstract
Cited by 1 Articles

Aim: Adenoid vegetation often causes open-mouth sleeping, snoring, breathing difficulties and it is also associated with many inflammatory diseases. In the treatment, adenoidectomy is performed to get rid of these symptoms and to prevent the future complications. In recent years, it has been reported that the neutrophil-to-lymphocyte ratio (NLR) is a prognostic factor in various diseases. Researches on the basophil-to-lymphocyte (BLR) ratio have been increasing. The aim of our study is to compare NLR and BLR before and after adenoidectomy and to determine whether these markers can be used as prognostic factors.
Material and Methods: The patients 2 to16 years old who underwent adenoidectomy in our clinic from January 2016 to June 2019 were included in our study. The postoperative hospital application data of them were analyzed. Routine hemograms for surgery and postoperative hemograms (except inflammatory conditions) were used for calculating the NLR and BLR.
Results: One hundred and twelve patients were included in the study. When the preoperative and postoperative NLR values (1.3335 and 1.1152, respectively) were compared, there was a statistically significant decrease in the postoperative period (p = 0.02). However, when the BLR values were compared preoperatively and postoperatively (0.0054 and 0.0050, respectively), there was no statistically significant difference in the postoperative period (p = 0.59).
Conclusion: There are very few studies in the literature that evaluates NLR before and after adenoidectomy. To our knowledge, our research is the first study to evaluate BLR before and after adenoidectomy. In contrast to the literature, a significant difference in NLR was found out in our study. It has been determined that NLR can be used as a prognostic marker in adenoidectomy. More researches are needed for BLR in this area.

Key words: neutrophil-to-lymphocyte ratio; basophil-to-lymphocyte ratio; adenoidectomy






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