Background: Prevalence of heart failure in asymptomatic type 2 DM subjects is increasing. Presence of microvascular complications like retinopathy and microalbuminuria, is under evaluation for predicting cardiovascular complications like heart failure in type 2 DM subjects. Aims and objectives: To study the relation between diabetic retinopathy and microalbuminuria with presence and grades of diastolic dysfunction in type 2 diabetes mellitus (DM) subjects. Materials and methods: This was a cross-sectional, observational study. A total of 62 subjects with type 2 diabetes mellitus (Type-2 DM) were enrolled. Fundoscopy examination for diabetic retinopathy, urine for microalbuminuria and standardized transthoracic echocardiographic (TTE) examination were performed. Left ventricular diastolic dysfunction (LVDD) was labeled if â‰¥3 of variables were present: "Septal e 34 mL/m2, Peak TR velocity >2.8 m/sec. Results: The peak early trans-mitral filling wave velocity (E) was low in subjects with diabetic retinopathy [40 ± 11.6 cm/s vs 46 ± 9.6cm/s]. Mean of E/A ratio in subjects with diabetic retinopathy group was significantly lower compared to those without retinopathy (‘p’ < 0.03). The E/e’ ratio was significantly higher in subjects with retinopathy (15.7 ± 2.48 vs 13.24 ± 1.88, p
Diabetic retinopathy, microalbuminuria, Left ventricular diastolic dysfunction, LVDD, E/A ratio, E/e ratio
Exosome treatment for stroke with diabetic comorbidity.
Venkat P, Chopp M
Neural regeneration research. 2022; 17(2): 315-317
Health-seeking behaviour, views and preferences of adults with suspected increased intestinal permeability: A cross-sectional survey of Australian adults.
Leech B, McIntyre E, Steel A, Sibbritt D
Integrative medicine research. 2022; 11(1): 100757
Neutrophil-to-lymphocyte ratio in sporadic amyotrophic lateral sclerosis.
Wei QQ, Hou YB, Zhang LY, Ou RW, Cao B, Chen YP, Shang HF
Neural regeneration research. 2022; 17(4): 875-880
Diabetic retinopathy: neurovascular disease requiring neuroprotective and regenerative therapies.
Neural regeneration research. 2022; 17(4): 795-796
Mitochondrial dysfunctions in neurodegenerative diseases: role in disease pathogenesis, strategies for analysis and therapeutic prospects.
Rey F, Ottolenghi S, Zuccotti GV, Samaja M, Carelli S
Neural regeneration research. 2022; 17(4): 754-758