2.8 m/sec. Results: The peak early trans-mitral filling wave velocity (E) was low in subjects with diabetic retinopathy [40 11.6 cm/s vs 46 9.6cm/s]. Mean of E/A ratio in subjects with diabetic retinopathy group was significantly lower compared to those without retinopathy (p < 0.03). The E/e ratio was significantly higher in subjects with retinopathy (15.7 2.48 vs 13.24 1.88, p" />
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Review Article

JCR. 2020; 7(5): 981-986


RELATION OF RETINOPATHY AND MICROALBUMINURIA WITH DIASTOLIC DYSFUNCTION IN SUBJECTS WITH TYPE 2 DIABETES MELLITUS

Virendra C. Patil, Akshay R. Kulkarni, Harsha V. Patil.

Abstract
Background: Prevalence of heart failure in asymptomatic type 2 DM subjects is increasing. Presence of microvascular complications like retinopathy and microalbuminuria, is under evaluation for predicting cardiovascular complications like heart failure in type 2 DM subjects. Aims and objectives: To study the relation between diabetic retinopathy and microalbuminuria with presence and grades of diastolic dysfunction in type 2 diabetes mellitus (DM) subjects. Materials and methods: This was a cross-sectional, observational study. A total of 62 subjects with type 2 diabetes mellitus (Type-2 DM) were enrolled. Fundoscopy examination for diabetic retinopathy, urine for microalbuminuria and standardized transthoracic echocardiographic (TTE) examination were performed. Left ventricular diastolic dysfunction (LVDD) was labeled if ≥3 of variables were present: "Septal e 34 mL/m2, Peak TR velocity >2.8 m/sec. Results: The peak early trans-mitral filling wave velocity (E) was low in subjects with diabetic retinopathy [40 11.6 cm/s vs 46 9.6cm/s]. Mean of E/A ratio in subjects with diabetic retinopathy group was significantly lower compared to those without retinopathy (p < 0.03). The E/e ratio was significantly higher in subjects with retinopathy (15.7 2.48 vs 13.24 1.88, p

Key words: Diabetic retinopathy, microalbuminuria, Left ventricular diastolic dysfunction, LVDD, E/A ratio, E/e ratio



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