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JCDR. 2021; 12(4): 2293-2303

Effect of Diabetes Mellitus without Vascular Changes on Maternal and Fetal Outcomes

Ali EL-Shabrawy Ali, Anwar Ezzat Esmael, Ruwaydah Abuojaylah Ali ALbakoush, Safaa Abdelsalam Ibrahim.


Background: Diabetes Mellitus is a metabolic disorder characterized by the presence of hyperglycemia due to defective insulin secretion, defective insulin action or both. This study aimed to assess the effect of different types of diabetes mellitus without vascular changes on maternal and fetal outcomes. Patients and methods: A cross-sectional study was carried out in Zagazig University Maternity Hospital during the period from March until September 2019. Included 50 cases of gestational and pregestational diabetic pregnant women. Patients were randomly divided into two groups of 25 patients, group I: included 25 pregnant women with pregestational diabetes mellitus (Type 1and Type 2 DM) without vascular changes. Group II: included 25 pregnant women with gestational diabetes mellitus. Fasting 2h postprandial blood glucose level was done and HbA1c. Complete general and abdominal examination, Obstetric Ultrasonography was done for all patients with Umbilical and middle cerebral artery Doppler if needed. Results: There was no statistically significant difference in gestational age at delivery and mode of delivery in current pregnancy between the two groups. There was statistically significant difference in fasting blood glucose and HbA1C between the two groups. However, regarding postprandial blood glucose, there was no statistically significant difference. Conclusion: We concluded that either diabetes was gestational or pregestational there was no statistical difference between maternal and fetal outcomes

Key words: Pregestational diabetes; GDM; Fetal outcomes

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