Adenostemma is a genus in the Asteraceae family, which consist of more than 20 species distributed in the tropical region of Asia, Africa, Australia, America, and the Pacific Islands. They have been used in folk medicine as remedies for diseases such as fever, inflammation, edema, digestive disorders, and lung injury. This review aims to provide information about Adenostemma’s species, traditional uses, chemical constituents, and therapeutic potential based on scientific evidence. The literature search was carried out through Google Scholar, PubMed, ScienceDirect, and KNApSAcK Family using various search terms. Our studies revealed that Adenostemma species has various secondary metabolites, including alkaloids, terpenoids, phenolics, flavonoids, fatty acids, saponins, and tannins. Scientific evidence on its extracts and isolated compounds showed antioxidant, anti-inflammatory, anti-melanogenic, antitumor, and antiviral activities. That investigation showed Adenostemma species offer a prospective source for new drug development. However, the phytochemical and pharmacological data are currently limited and need further studies.
Key words: Adenostemma; species; traditional uses; chemical compounds; pharmacological activities; health
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