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Review Article

. 2017; 8(1): 1-5

Comprehensive Approach to Congenital Heart Defects

Huliyurdurga Srinivasa Setty Natraj Setty, Shivanand Sanganna Gouda Patil, Raghu Thagachagere Ramegowda, Vijaykumar, Iswarappa Balekundre Vijayalakshmi, Cholenahalli Nanjappa Manjunath.

Congenital heart defects (CHD) are cardiovascular malformations that generally occur due to aberrant development of a
normal structure in the fetus, or failure of such a structure to progress beyond an early stage of embryonic or fetal development.
Malformations are due to complex multi-factorial genetic and environmental causes. Congenital heart defects,
in a definition proposed by Mitchell et al, is a gross structural abnormality of the heart or intrathoracic great vessels that
are actually or potentially of functional significance. A comprehensive approach to every aspect of CHD, covering from
embryology, fetal malformations, pathology, clinical approach, investigations, interventions to the surgery is very essential
to reduce the morbidity and mortality in children with CHD.

Key words: Congenital malformation, Great vessels, Fetus, ASD,VSD,TOF.

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American Journal of Physiology, Biochemistry and Pharmacology


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