Objective: To examine and evaluate the predominant and common etiologic agent(s) of
urinary tract infection (UTI) in Sukkur city and to determine their current antibiotic
susceptibility/resistance trends.
Methods: Nine hundred sixty six patients out of 1430 abnormal urine reports (showing
significant abnormalities such as protein, pus, red cells) were asked to give second
sample. The urine samples were examined by both urine test strip (Combur 10 Test,
Roche) and microscopically (wet preparation) followed by culture and sensitivity. The
culture sensitivity was done on urine samples of which bacterial numbers were estimated
as more than 105CFU. The study was conducted at Safeway Diagnostic and Research
Laboratory Sukkur and the Department of Microbiology, Shah Abdul Latif University
Khairpur, Sindh from March 2001 to March 2003.
Results: Eight hundred fifty-two (88.2%) showed Escherichia spp followed by
Klebsiella spp (6.9%) and proteus spp (4.9%). These showed 95%, 90%, 90% sensitivity
to ofloxacin respectively. Ninety percent isolates of Escherichia spp, Proteus spp and
Klebsiella spp were sensitive to ciprofloxacin.
Conclusion: Escherichia spp was found to be major uropathogen and ofloxacin and
ciprofloxacin were effective antibiotics against these strains isolated from UTI patients of
Sukkur city. (Rawal Med J 2007;32:99-101).
Key words: Urinary tract infections, Uropathogens, Antibiotics, E coli
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