Home|Journals|Articles by Year Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Article

JVS. 2019; 6(1): 93-101


Cytokines profile and antibody response of calves vaccinated with conventional inactivated Trivalent FMD vaccine

Abdelaziz Abdelnasser Yassin,Ayman Hanea El Deeb,Abeer Ezzat Mansour,Hussein Aly Hussein.

Abstract
In the present study, eight (sero-negative for FMDV) native breed calves (6-12 months of age) were used to study the cytokine profile including IL-2, IL-4, IFN-γ and antibody response of calves vaccinated with conventional inactivated trivalent FMD vaccine. Expression of Th1 and Th2 was determined using quantitative ELISA. Results reveled peaks of IL-4 at 7th day, IFN-γ at 14th day and IL-2 at 21st day post vaccination.
Lymphocytic proliferation assays demonstrated the continuous response of lymphocytes started at the 3rd day till reaches peak at 28th day post vaccination then start to decline. Whereas the peak titers for antibodies were reported at the 28th day post vaccination. Indeed, the study reports the role of ail adjuvant in stimulating the cellular response for inactivated vaccine.

Key words: FMD, Cytokines, MTT, VNT and cross-protection


Full-text options

Full-text Article




Advertisement
American Journal of Physiology, Biochemistry and Pharmacology

SUBMIT YOUR ARTICLE NOW




ScopeMed.com
BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.