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IJMDC. 2026; 10(8): 2416-2428 Comparison of very early mobilization (less than 24 hours), early mobilization (24-48 hours), and standard mobilization (more than 48 hours) in improving the functional outcomes in acute stroke: a systematic reviewMohammad N. Almotiri, Mohammed Yousef Almohaimeed, Mohammed N. Aljabr, Juwan Mohammed Almutairi, Shefa Owaiyedh Almutairi, Ahmad Khalaf Alanazi, Emad Abdulaziz Yousef Alhoody, Ghazi Ibrahim A. Alromayan, Oabdh Abdulaziz Ibrahim Almushiqh. Abstract |  Download PDF | |  Post | Strokes continue to be one of the main causes of chronic disability and mortality globally. However, the optimal mobilization time after stroke onset remains contested. This systematic review and meta-analysis aimed to compare the effectiveness and safety of very early (48 hours) mobilization protocols in terms of achieving good functional outcomes, motor improvement, reducing length of hospital stay, and safety in acute stroke patients. A systematic literature search was conducted in major databases for relevant literature published up to 2025. A total of 21 studies were analyzed. Very early mobilization (VEM) (
Key words: Stroke, early mobilization, very early mobilization, functional outcomes, systematic review
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