Introduction: Polymorphous adenocarcinoma (PAC) is almost entirely related to minor
salivary glands. Mostly found in the palatal region but on rare it was also observed in other
intraoral areas. Histopathologically Polymorphous adenocarcinoma is non-encapsulated and shows infiltrative borders. Morphologically there are different growth patterns responsible for difficulty in diagnosis and confusion with other salivary gland tumours. In recent studies it is observe that there is a potential for histological transformation of the lesion from low to high grade malignancy.
Case Report: A 52 year old male reported to Memon Medical Institute Hospital dental OPD with growth on hard plate for 6 months and mobility of teeth. The lesion was painless with no signs of ocular involvement. Lesion was extending from premaxillary region covering whole of the hard palate to soft palate and beyond. CT scan shows heterogenous enhancing mass with calcifications probably arising from alveolar process of left upper jaw causing complete destruction of left alveolar processes with maxillary bone and hard palate. A plan for total maxillectomy discussed with the patient and the defect will be filled with a hollow acrylic obturator.
Discussion: Polymorphous Adenocarcinoma (PAC) is an uncommon tumour and mostly related to minor salivary glands. We describe here a case report of PAC arising from minor salivary glands of the palate. Our case showed different radiographic features that was resembled to slow growing tumour but aggressive in nature. In most of cases excision with wide margin is recommended, but in some cases modified radical neck dissection is indicated. Recurrences may occur after a long period, so for prevention prolonged follow up is recommended.
Key words: Adenocarcinoma, Palate, Salivary glands, Tumour.
Key words: PAC, Adenocarcinoma, Palate, Salivary glands, Tumour
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