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Original Research



Histopathological study of 26 rare skin adnexal tumours over 5 years – a diagnostic dilemma!

Sadaf Alam, Misbah Lateefa, Raghumani Mohanty.




Abstract

Background: Skin adnexal tumors (SATs) are rare in Indian subcontinent and hence pose difficulty in diagnosis as they may histopathologically look like more common skin malignancies in this region. Several studies on SATs have been carried out in Western countries but very few in this region.

Objective: To correlate SATs with age, sex, and location and determining its incidence in the Department of Pathology at Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha and to address dilemmas in diagnosing them.

Materials and Methods: A total of 26 cases were included in this study from January 2010 to June 2015 with respect to incidence of adnexal tumors, age, and sex distribution. All slides were stained with hematoxylin and eosin and then findings were corroborated with special stains such as PAS and reticulin wherever required.

Result: Of all, 92.31% (24/26) were benign and 7.69% (2/26) were malignant adnexal tumors. The sebaceous gland tumors constituted the largest group (42.31% 11/26) cases followed by the sweat gland tumor (34.62%, 9/26) cases and hair follicle tumor (23.10%, 6/26) cases. Overall male:female ratio was 1.16:1. The most common age group was 40–49 years and the commonly affected body part was head and neck region (61.53%, 16/26) followed by trunk (15.38%, 4/26). Eccrine poroma, sebaceous hyperplasia, and pilomatricoma were the most common benign tumors and two sebaceous carcinoma were the only two malignant tumors seen.

Conclusion: The incidence of benign skin adnexal tumors was more as compared to the malignant tumors. Malignant tumors were seen in older age.

Key words: skin adnexal tumors histopathology immunohistochemistry age sex






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