Objective: Preeclampsia is a pregnancy-specific, multisystem disorder characterized by the development of hypertension and proteinuria 20 weeks after gestation. We investigated the role of mean platelet volume in preeclampsia according to the emergence of the disease, as being early or late, and its severity.
Material and Methods: Forty-six preeclamptic women and 49 healthy pregnant women as the control group were included in this retrospective study. Preeclamptic patients were divided into groups. Age, hemoglobin count, hematocrit, platelet count, mean platelet volume, platelet distribution width, and pregnancy weeks of the groups were compared with each other.
Results: The mean age of the groups was similar (preeclampsia=30±6.9 and control=28.4±5.3, p=0.125). There was no statistically significant difference between the two groups in terms of gestational weeks (P=0.2). The mean platelet count (x103/μL) was 207±83 in the preeclamptic group and 205±51 in the control group and there was no statistically significant difference between the groups (P=0.78). It was found that the mean platelet volume was notably higher in the preeclamptic group (10.8±1.3 and 9.8±1.3, respectively) (P=0.03). The platelet distribution width values of the preeclamptic group and the control group were 15.3±2.8 and 14.8±2.5, respectively, and there was no statistically significant difference between the groups (P=0.34).
Conclusion: Mean platelet volume was higher in the preeclamptic group than the control group. However, as far as mean platelet volume is concerned, there were no differences between the emergence of preeclampsia as early or late, or the severity of preeclampsia.
Key Words: Preeclampsia; Mean platelet volume; Severity of preeclampsia; Subclassification of preeclampsia.
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