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Ann Med Res. 2003; 10(1): 5-9


Pharmacological Ureteral Dilation With İntraluminal Papaverine Administration

Ali Güneş*, Tahir Zengin*, Uğur Yılmaz*, Ahmet Soylu*, Y.Murat Uğraş*, M. Derya Balbay**

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Abstract


 

Prior to ureterorenoscopy procedures, dilation of ureteral orifice and intramural ureter is recommended. Cone tip

metallic bougies and balloon dilators are frequently used for this purpose. In the present study, dilating effect of

intraluminal papaverine administered through a Swan-Ganz catheter placed in the ureteral orifis has been studied.

Twenty patients undergoing elective endourologic surgery, having normal collecting systems, were included. To

the right ureter, 240 mg papaverine (8cc) + iopamidol (2cc) and to the left 8cc physiological saline + 2cc

iopamidol were administered simultaneously within 5 seconds. Following the administration of radioopaque

materials into both ureters, fluoroscopic ureteral diameters and intraluminal pressures were measured at zero, 5th

and 10th minutes. The results were compared for diameter and pressure changes in the papaverine administered

and control sides.

In papaverine administered side, a statistically significant decrease in intraluminal pressure and increase in ureteral

diameter at 5th and 10th minutes have been found (p






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