Home|Journals|Articles by Year|Audio Abstracts
 

Original Article



Chromanone-type compounds from marine sponge-derived Daldinia eschscholtzii KJMT FP 4.1

Mada Triandala Sibero,Tao Zhou,Yasuhiro Igarashi,Ocky Karna Radjasa,Agus Sabdono,Agus Trianto,Tiara Ulfa Bachtiarini,Muhammad Syaifudien Bahry.




Abstract
Cited by 14 Articles

The investigation on chemical diversity of secondary metabolites from marine microorganisms, a sponge-derived fungus was found to produce a glycosylated aromatic compound, Karimanone (1). The fungal strain was isolated from an Indonesian sponge Xestospongia sp. collected in Karimunjawa National Park, Central Java, Indonesia, and was identified as Daldinia eschscholtzii based on the ITS rRNA gene sequence. Herein, we describe the isolation and characterization of karimanone (1), a new chromanone-type compound along with three biosynthetically related metabolites 2 – 4. All compounds were active against a multidrug-resistant strain of Salmonella enterica ser. Typhi with an MIC of 62.5 μg/mL for 2 and 125 μg/mL for 1, 3, and 4.

Key words: Daldinia, chromanone, sponge-associated fungus






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.