Objective: To analyze the functional and oncological outcomes of custom made endoprosthesis following distal femur tumor resection over a period of 6 years.
Methodology: We reviewed 35 bone tumor cases operated upon between April 2003 and February 2009 to study the 6 years follow-up results. There were 20 women and 15 men with a mean age of 24 (range 14-65 years). There were 28 primary malignant distal femur tumors, four aggressive benign distal femur tumors (Giant Cell Tumor /G.C.T), and three metastasis (primary malignancies were renal and lung). Overall 23 patients received neoadjuvant chemotherapy. Twenty-five patients received adjuvant additional chemotherapy. Post-operative follow-up phase of the patients was performed through out-patient clinic, medical files or phone call basis. Patients were examined for complications, oncological and functional outcomes.
Results: Among the 35 patients, there were 15 deaths (42.9%) and 20 survivals (57.1%) at their individual sixth year follow-up. The Musculoskeletal Tumor Society (MSTS) functional rating at their individual sixth year follow up was excellent in 13 patients (65%), good in five (25%), fair in one (5%) and poor in one (5%).
Conclusion: Limb salvage surgeries for distal femur bone tumors through the introduction of custom made endoprosthesis in our service improved the outcome and decreased the mortality and morbidity of the patients.
Key words: Limb salvage, bone tumors, tumor resection, distal femur, endoprosthesis
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