Home|Journals|Articles by Year|Audio Abstracts
 

Original Research

Egypt. J. Exp. Biol. (Zoo.). 2008; 4(0): 81-88


HEMATOPORPHYRIN TOXICITY IN THE CULTURED OREOCHROMIS NILOTICUS

Khalid H. Zaghloul, Essam M. Hassan, Mahmoud H. Abdel Kader.




Abstract

The toxic effect of photosensitizers in particularly hematoporphyrin (HP), photo-pesticides, has been investigated. The results indicated that the 96 hrs LC50 of HP to Nile tilapia, Oreochromis niloticus was 0.4 X 10-5 Mol/l in case of fry fish (2 g) and 0.2×10-3 Mol/l in case of adult fish (50 g). Exposure of adult Oreochromis niloticus to HP lethal concentration (0.2×10-3 Mol/l) for 96 hours and sublethal concentration (0.2×10-4 Mol/l) for 12 weeks, revealed damage in gills, liver and kidney tissues. A significant decrease (at P < 0.01) in growth indices, RBCs, Ht, Hb, serum total protein and total lipids but significant increase (at p < 0.01) in WBCs, glucose level, serum AST, ALT. AP, creatinine and uric acid, in addition to meat quality deterioration (decrease in muscle total protein and total lipids with an increase in muscle water content) compared to that of control fish group were also investigated. The study implies the importance of previous knowledge about the susceptibility of fish and its reproductive season before usage of HP in environmental applications.

Key words: Hematoporphyrin, Oreochromis niloticus , Blood picture. Meat quality






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.