Objectives: There is no daily practical method for the diagnosis and follow-up of PPROM. In this study, our goal is to examine the association between PPROM and platelet/lymphocyte (PLR) and neutrophil//lymphocyte (NLR) ratios.
Material and Method: Eighty women with a diagnosis of PPROM between 24th and 34th weeks of gestation were included in the study. Eighty three women without membrane rupture between the same gestational weeks constituted the control group. Information about the women including in the study was collected retrospectively from hospital medical records. For each patient, gravida, parity, age, week of gestation, week of birth, and mode of delivery were examined. To evaluate perinatal outcomes, gender, 1st and 5th minute Apgar scores, birth weight and neonatal death were examined. The patients' white blood cell, lymphocyte neutrophil and platelet counts, platelet/lymphocyte, neutrophil/lymphocyte ratios and hemoglobin, c-reactive protein values were examined.
Results: The mean NLR of the PPROM group was 30.96±2.55(mean±sd) and mean PLR was 148.06±72.18(mean±sd). In the control group, these values were calculated as 30.91±2.43(mean±sd) and 126.74±45.85(mean±sd), respectively. Both rates were higher in the PPROM group (p=0.026).
Conclusion: The platelet/lymphocyte and neutrophil/lymphocyte ratios were higher in the study group. Therefore, PLR and NLR can be utilized in the management of PPROM.
Key words: Keywords: Preterm premature rupture of fetal membranes, neutrophl/lymphocyte ratio, platelet/lymphocyte ratio
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