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Importance of high triglycerides as a cardiovascular risk factor in Indian diabetic population – A review

Hiren Pandya.




Abstract

Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder characterized by a state of chronic hyperglycaemia which may lead to various disabling and life-threatening macrovascular and microvascular complications resulting in reduced quality of life and premature mortality. As per many recent evidences, Cardiovascular disease (CVD) is a major cause of morbidity and mortality in these individuals and is responsible for 70-75% of deaths in diabetes population. India is carrying almost 65 million diabetic populations with almost 77 million populations with pre-diabetes. Majority of diabetes patients suffers from dyslipidaemia. Dyslipidaemia in diabetes is usually a mixed type of hyperlipidaemia, i.e. elevated small dense LDL, high TG and low HDL-C. This pattern of dyslipidaemia is also termed as an Atherogenic Diabetic Dyslipidaemia (ADD). Current evidences suggest that elevated TG is an important independent risk factor for future CV risk.

Key words: Diabetes; Dyslipidaemia; Triglycerides; Cardiovascular Risk






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