In patients with primary hyperparathyroidism, complete surgical resection of all hyperfunctioning parathyroid tissue is essential. The aim of this study was to evaluate the success rates of minimally invasive parathyroidectomies for primary hyperparathyroidism performed after localization studies with 99mTc-sestamibi (MIBI) scintigraphy and neck ultrasonography (USG). And also, we aimed to determine the factors affecting the success rate in surgery. Retrospective analysis of 58 consecutive patients with a diagnosis of primary hyperparathyroidism who underwent parathyroidectomy between January 2018 and December 2021 in our institution. The patients were evaluated according to Miami criteria and divided into two groups as successful or unsuccessful surgery. Demographic and clinical characteristics of the patients were obtained from hospital records. Surgical success was achieved in 50 (86.2%) of the 58 patients included in the study. In both groups, neck USG and MIBI scintigraphy showed the same localization for the lesion in a correlated manner. The clinical complaints of the patients, preoperative PTH, Ca and 24-hour urinary Ca levels were similar in both groups. In 10 (17.2%) patients, inconsistency in localization was found between USG and MIBI scintigraphy, and surgical failure was found in 4 (40%) of these patients. Surgical failure was statistically significant in patients with inconsistency in localization between USG and MIBI scintigraphy. The sono-scintigraphic scan concordance increases surgical success rates in cases where minimally invasive parathyroid surgery is planned. If there is an inconsistency between USG and MIBI, preoperative four dimentional computed tomography, intraoperative rapid PTH, gamma probe or frozen method can be used. It should be kept in mind that multiple gland pathologies may be more common in addition to solitary adenoma in lesions smaller than 1 cm in USG. In addition, in these cases, as the diagnostic value of scintigraphy is low, surgical success will also decrease.
Key words: Primary hyperparathyroidism, minimal invasive parathyroidectomy, tc-99m methoxyisobutylisonitrile scintigraphy, neck ultrasonography
|
