Objective
The purpose of this study is to report our experience with a comprehensive view of patients hospitalized in tertiary level center with a diagnosis of infective endocarditis.
Methods
Medical records of patients who were hospitalized with a diagnosis of infective endocarditis were reviewed by using hospital database, retrospectively. Surgical intervention, occurrence of complications, in-hospital and 30-day mortality data were noted.
Results
A total of 53 patients (58.5% male) were included in this single center, retrospective study. Native valve endocarditis was more common (86.8%) and located in mitral position. Seven patients have mechanical prothestetic valve infection, those were also in mitral position. Most of the patients (92.4%) had vegatation size greater than 10 mm. Thirty-one patients (58.5%) had culture negative endocarditis while Staphylococcus Aureus was the most common (9.4%) cultured organism. In-hospital or 30-day mortality was found 35.8%. Rate of embolism was 45.3%. Risk factors associated with mortality include older age, lower body mass index, being in NYHA III/IV status, development of acute renal failure and embolic phenomenon, septic shock, congestive heart failure, and presence of tricuspid regurgitation higher than moderate. Early valve surgery seems to improve the prognosis of IE according to our findings.
Conclusion
Older age, lower BMI, being in NYHA III/IV status, previous history of hypertension, presence of tricuspid valve regurgitation higher than moderate degree, occurrence of acute renal failure, embolic phenomenon, septic shock, congestive heart failure was found risk factors for mortality. Early valve surgery seems to improve the prognosis of IE according to our study.
Key words: Infective Endocarditis; Prognosis; Heart Valve Disease
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