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Research Article

JIRLS. 2022; 4(1): 74-79


EVALUATION OF WOUND HEALING EFFECT OF Tamarindus indica METHANOL STEM BARK EXTRACT IN ALBINO RATS

Ukwuani-Kwaja AN; Muhammad L; Abba A;.




Abstract

Tamarindus indica Linn (Family: Caesalpiniaceae) is traditionally used for the treatment various ailments such as diarrhea, typhoid, diabetes, wounds and malaria. The present study is aimed at providing scientific validation for the wound healing potential of the crude extract of Tamarindus indica stem bark in the excision albino rats model. The crude extraction was done using 100% methanol and qualitative phytochemical analysis were carried out using the standard methods. Excision wound models were used to determine the wound healing activity of Tamarindus indica. Wounds were treated with ointment formulation of the extract (10% and 50% w/w) and penicillin cream for 24days.Phytochemical screening revealed the presence of flavonoids, alkaloids, saponnins, cardiac glycosides and quinones. The result showed significant (p

Key words: Wound healing, epithelisation, stem bark extract and wound contraction






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