Introduction: The ureters stent has side effects that the complaint is called stent-related syndrome (SRS). The complaint is equal to Lower Urinary Tract Symptoms (LUTS) and overactive bladder (OAB). Alpha-blocker and antimuscarinic therapy used for benign prostatic hyperplasia (BPH) and OAB therapy can also be used to reduce complaints of SRS. The purpose of this research is to determine the effectiveness of Tamsulosin 0.4 mg/day compared with Mirabegron 50 mg/day against changes in LUTS complaints in patients after the installation of the Ureteric Stent.
Methods: The design of this research uses a double-blinded experimental method. Samples taken randomly were 50 patients with Double-J (DJ) Stent post-installation LUTS complaints. Data collection is taking place from July to November 2019, using a tool measuring instrument ureteral stent symptom questionnaire (USSQ). Data were analyzed using SPSS 24.0. a P-value < 0.05 was considered to be statistically significant.
Results: In the entire patient group, the average age of respondents is 44.86 ± 11.85 year, in groups with Tamsulosin 5 mg/day treatment compared with Mirabegron 50 mg/day gives a good effect in lowering the complaint score LUTS during 4 weeks post-installation of Double-J (DJ) Stent, in this case, Urinary Symptoms, pain, general circumstances, work activity, and other complaints (P < 0.05). The average rate reduction of USSQ Urinary Symptoms, pain, general circumstances, greater work activity in the Tamsulosin group.
Conclusion: Tamsulosin Therapy 5 mg/day compared with Mirabegron 50 mg/day can effectively cure complaints of post-installation LUTS DJ Stent.
Key words: Stent-Related Symptoms, Tamsulosin, Mirabegron, USSQ
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