Home|Journals|Articles by Year|Audio Abstracts
 

Original Article



The Predictive Ability of Hematologic Parameters for In-hospital Mortality In Patients Presenting With Pulmonary Embolism

Sevgi Özcan,Esra Dönmez.




Abstract

Introduction
Acute pulmonary embolism (PE) is one of the leading causes of mortality. Components of complete blood count indicate thrombotic and/or inflammatory status in various clinical conditions. In this study, we aimed to evaluate if hematological parameters could predict in-hospital mortality in patients presenting with PE.
Methods
Patients hospitalized with a diagnosis of acute PE in our tertiary center between 2016 and 2022 were involved in this retrospective study. Hematologic parameters obtained on admission were analayzed. PESI scores were calculated and comparative statistical and regression analyses were obtained.
Results
There were 254 patients (37.4% male). Thirty-eight patients (14.9%) were died in-hospital and formed ‘non-survivors’ group. NLr and RDW were found as independent risk factors associated with in-hospital mortality. Our results revealed a strong correlation between hematological parameters and PESI risk score and a cut off value of 5.9 for NLr was associated with 68.4% sensitivity and 68.1% specificity; besides that, cut off value of 14.1 for RDW was associated with 68.4% sensitivity and 62.6% specificity in prediction of in-hospital mortality.
Conclusion
Our current study showed that hematological parameters, assessed by routine blood count analysis, may serve as a promising and useful marker to foresee in-hospital mortality in patients presenting thru acute PE especially when used additive to validated risk scores.

Key words: Neutrophil/lymphocyte ratio (NLr); Platelet distribution width (PDW); Pulmonary embolism: Red cell distribution width (RDW)






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.