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Case Report



A rare clinical case report of recurrent angiolymphoid hyperplasia with eosinophilia of hand treated by intralesional steroids following surgical excision: when a traditional therapy is still up to date

Rashmiranjan Sahoo, Amitkumar Bose, Nalini Naik, Sreekanth Gorre, Abhinav Voona, Akanksha Kanungo.




Abstract
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Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon idiopathic benign vascular disorder. Angiolymphoid hyperplasia with eosinophilia most often affects the head and neck, with involvement of other areas such as the hands occurring rarely. ALHE may affect people of any colour; however, it is more common among Asians. Mostly, it affects young to middle-aged women, presenting as fleshy/plum-coloured pruritic nodules and papules. The histological examination indicates dense inflammation, predominantly lymphocytes, forming aggregate and reactive follicles with a germinal center, and many proliferative capillaries intermingled with the inflammatory cells along with eosinophils. A 21-year-old female presented with a distinct and coalescent erythematous nodular lesion in the right forearm for 5 months. The histopathological study was consistent with ALHE. Intralesional corticosteroid injections were performed monthly for six months, and complete remission was accomplished. The goal of this rare case report is to notice and consider this rare clinical picture, review, and analyze various diagnostic methods, differential diagnoses, and treatment modalities.

Key words: Angiolymphoid hyperplasia with eosinophilia,Benign vascular disorder, Kimura disease, Epithelioid hemangioma, Intralesional corticosteroids, Triamcinolone






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