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Original Research

RMJ. 2020; 45(4): 762-765


Relationship between Atrial fibrillation and plasma omentin-1 levels in patients with coronary artery disease

Shazia Nazar, Sitwat Zehra.




Abstract

Objective: To correlate the plasma omentin-1 with the presence of atrial fibrillation in patients with coronary artery disease (CAD).
Methodology: This cross-sectional study was performed at cardiac unit of Civil Hospital Karachi, Pakistan, from June 2016 to March 2017. A total of 195 patients of coronary artery disease, and 150 without atrial fibrillation (AF) were included in the study. Diagnosis of AF was made on the basis of electro-cardio-graph. Plasma omentin-1 levels were determined by enzyme linked immuno- sorbent assay. Data were analyzed by using SPSS version 16.
Results: Out of the 195 patients of AF (37 with permanent, 63 with persistent and 76 with paroxysmal AF), it was found that CAD patients with AF had reduced plasma omentin-1 levels (59.2±9.10 vs. 96.9±11.7, p

Key words: Atrial fibrillation, coronary artery disease, omentin-1.






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